Active Recombinant Cynomolgus TGFB1 Protein, His-tagged
Cat.No. : | TGFB1-1215C |
Product Overview : | Recombinant cynomolgus TGFB1 (Met1-Ser390) was expressed with a polyhistidine tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Cynomolgus |
Tag : | His |
Predicted N Terminal : | Leu 30 |
Form : | Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol. |
Bio-activity : | 1. Measured by its binding ability in a functional ELISA. 2. Immobilized Cynomolgus TGFB1-His at 10 μg/mL (100 μL/well) can bind Cynomolgus TGFBR2-Fc. The EC50 of Cynomolgus TGFBR2-Fc is 28-56 ng/mL. |
Molecular Mass : | The recombinant cynomolgus TGFB1 consists 372 amino acids and predicts a molecular mass of 42.7 kDa. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | TGFB1 transforming growth factor beta 1 [ Macaca fascicularis ] |
Official Symbol : | TGFB1 |
Synonyms : | transforming growth factor beta 1; transforming growth factor, beta 1 |
Gene ID : | 102129546 |
mRNA Refseq : | |
Protein Refseq : | |
MIM : | |
UniProt ID : | |
Chromosome Location : | chromosome: 19 |
Pathway : | AGE-RAGE signaling pathway in diabetic complications, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionTGFB1 stimulates the activity of cells involved in bone formation (osteoblasts) and plays a role in regulating bone resorption by influencing osteoclast function.
Potential side effects of anti-TGFB1 therapies may include immune system suppression, gastrointestinal issues, and skin reactions.
TGFB1 levels have been studied as potential biomarkers for diseases like cancer and fibrosis, aiding in diagnosis and monitoring disease progression.
TGFB1 plays a critical role in wound healing by stimulating the formation of new blood vessels, promoting the production of extracellular matrix, and aiding in the migration of cells to the wound site.
TGFB1 can induce the production of excessive extracellular matrix proteins, leading to tissue scarring and fibrosis in organs such as the liver, lung, and kidneys.
Customer Reviews (3)
Write a reviewThe impressive performance of the TGFB1 protein both in ELISA assays and protein electron microscopy structure analysis makes it a highly versatile and recommended choice for scientists across various disciplines.
Its reliability and efficacy in generating high-quality data make it an indispensable tool in the quest for unraveling the mysteries of protein structure and function.
The TGFB1 protein's excellent performance in ELISA ensures accurate and reproducible results, enhancing the reliability of experimental data.
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