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Recombinant Equine Interleukin 5 (Colony-Stimulating Factor, Eosinophil)

Cat.No. : IL5-257E
Product Overview : Recombinant Equine IL-5 was expressed inYeast. MW= 12.9 kDa (114 aa).
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  • Gene Information
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Cat. No. : IL5-257E
Description : Interleukin 5 (IL-5) plays an important role in B cell development by inducing the terminal differentiation of late-developing B cells. Additionally, IL-5 regulates the differentiation, survival and degranulation of eosinophils. IL-5 is expressed predominately by T-lymphocytes and mast cells, and to a lesser extent by eosinophils, natural killer cells and endothelial cells.
Source : Yeast.
Formulation/ Reconstitution : Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purification : Ion-exchange chromatography.
Purity : >95% as visualized by SDS-PAGE analysis.
Amino Acid Sequence : AVESPMNRLV AETLTLLSTH RTLLIGDGNL MIPTPEHKNH QLCIEEVFQG IDTLKNQTVQ GDAVAKLFQN LSLIKGYIDL QKKKCGGERW RVKQFLDYLQ EFLGVINTEW TIEG.
Bioactivity : In testing.
Stability And Storage : Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Gene Name : IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Equus caballus ]
Synonyms : interleukin 5 (colony-stimulating factor, eosinophil); IL5; IL-5; interleukin 5; TRF; T-cell replacing factor; interleukin-5; eosinophil differentiation factor
Gene ID : 100034199
mRNA Refseq : NM_001082499.1
Protein Refseq : NP_001075968.1
UniProt ID : O02699
Chromosome Location : 14
Pathway : Allograft rejection; Asthma; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Intestinal immune network for IgA production; Jak-STAT signaling pathway; T cell receptor signaling pathway

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Which effect of IL5 in the treatment of tuberous sclerosis? 08/07/2022

Inhibit the creatinine kinase level in the blood of patients with tuberous sclerosis, reduce the inflammatory response, and improve the quality of life of patients.

Does there have any effect of IL5 in the treatment of allergic rhinitis? 07/07/2022

IL5 can reduce the number of eosinophils in the nasal mucosa of patients with allergic rhinitis, reducing the symptoms of allergic reactions, such as sneezing, runny nose and nasal congestion.

What is the main function of IL5? 03/04/2022

Stimulate the proliferation and differentiation of white blood cells, promote the function of the immune system, and is used to treat diseases such as asthma, allergic rhinitis, nodular sclerosis and some malignant tumors.

Does IL5 have side effects? 10/26/2019

Cause mild side effects such as headache, nausea, vomiting, and serious side effects such as allergic reactions if the dose is too large or allergic.

Can IL5 be administered orally? 07/24/2019

IL5 cannot be administered orally, only by injection or intravenous drip.

What is the effect of IL5 in the treatment of asthma? 02/14/2019

IL5 can reduce the number of eosinophils in the lungs of asthma patients, reduce the frequency and severity of asthma attacks, and improve the quality of life of patients.

Customer Reviews (3)

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Reviews
07/26/2022

    High efficacy and safety in clinical treatment.

    06/22/2022

      There are no structural or functional defects.

      01/31/2019

        The stability and activity are maintained well during long-term storage.

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