| Cat.: | CDTB-2179E |
| Cat.No.: | CDTB-2179E |
| Product Overview: | Recombinant Escherichia coli CDTB Protein (19-269 aa) is produced by E. coli expression system. This protein is fused with a 10xHis-SUMO tag at the N-terminal and a Myc tag at the C-terminal. Protein Description: Full Length of Mature Protein. |
| Description: | Part of the tripartite complex that is required for the CDT activity. CdtB exhibits a DNA-nicking endonuclease activity, and very probably causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement. |
| Source: | E. coli |
| Species: | E. coli |
| Tag : | His-SUMO-Myc |
| Form: | Tris-based buffer,50% glycerol |
| Molecular Mass: | 47.4 kDa |
| Protein length: | 19-269 aa |
| AA Sequence: | DLTDFRVATWNLQGASATTESKWNINVRQLISGENAVDILAVQEAGSPPSTAVDTGTLIPSPGIPVRELIWNLSTNSRPQQVYIYFSAVDALGGRVNLALVSNRRADEVFVLSPVRQGGRPLLGIRIGNDAFFTAHAIAMRNNDAPALVEEVYNFFRDSRDPVHQALNWMILGDFNREPADLEMNLTVPVRRASEIISPAAATQTSQRTLDYAVAGNSVAFRPSPLQAGIVYGARRTQISSDHFPVGVSRR |
| Purity: | > 90% as determined by SDS-PAGE. |
| Notes: | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage: | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration: | A hardcopy of COA with reconstitution instruction is sent along with the products. |
| Gene Name: | cdtB type III cytolethal distending toxin protein CdtB [ Escherichia coli Vir68 ] |
| Official Symbol: | CDTB |
| Synonyms: | cdtB; |
| Gene ID: | 8164729 |
| UniProt ID: | Q46669 |
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