Recombinant Full Length Human APOC2 Protein, C-Flag-tagged

• Cat.No.: APOC2-439HFL
• Product Overview: Recombinant Full Length Human APOC2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 8.9 kDa
• AA Sequence: MGTRLLPALFLVLLVLGFEVQGTQQ PQQDEMPSPTLLTQVKESLSSYWES AKTAAQNLYEKTYLPAVDEKLRDLY SKSTAAMSTYTGIFTDQVLSVLKGE ETRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein

Gene Information

• Gene Name: APOC2 apolipoprotein C2 [ Homo sapiens (human) ]
• Official Symbol: APOC2
• Synonyms: APO-CII; APOC-II
• Gene ID: 344
• mRNA Refseq: NM_000483.5
• Protein Refseq: NP_000474.2
• MIM: 608083
• UniProt ID: P02655