Recombinant Full Length Human CANX Protein, C-Flag-tagged

• Cat.No.: CANX-1595HFL
• Product Overview: Recombinant Full Length Human CANX Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 65.3 kDa
• AA Sequence: MEGKWLLCMLLVLGTAIVEAHDGHD DDVIDIEDDLDDVIEEVEDSKPDTT APPSSPKVTYKAPVPTGEVY FADSFDRGTLSGWILSKAKKDDTDD EIAKYDGKWEVEEMKESKLPGDKGL VLMSRAKHHAISAKLNKPFL FDTKPLIVQYEVNFQNGIECGGAYV KLLSKTPELNLDQFHDKTPYTIMFG PDKCGEDYKLHFIFRHKNPK TGIYEEKHAKRPDADLKTYFTDKKT HLYTLILNPDNSFEILVDQSVVNSG NLLNDMTPPVNPSREIEDPE DRKPEDWDERPKIPDPEAVKPDDWD EDAPAKIPDEEATKPEGWLDDEPEY VPDPDAEKPEDWDEDMDGEW EAPQIANPRCESAPGCGVWQRPVID NPNYKGKWKPPMIDNPSYQGIWKPR KIPNPDFFEDLEPFRMTPFS AIGLELWSMTSDIFFDNFIICADRR IVDDWANDGWGLKKAADGAAEPGVV GQMIEAAEERPWLWVVYILT VALPVFLVILFCCSGKKQTSGMEYK KTDAPQPDVKEEEEEKEEEKDKGDE EEEGEEKLEEKQKSDAEEDG
  GTVSQEEEDRKPKAEEDEILNRSPR NRKPRRETRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Antigen processing and presentation

Gene Information

• Gene Name: CANX calnexin [ Homo sapiens (human) ]
• Official Symbol: CANX
• Synonyms: CNX; P90; IP90
• Gene ID: 821
• mRNA Refseq: NM_001746.4
• Protein Refseq: NP_001737.1
• MIM: 114217
• UniProt ID: P27824