Recombinant Full Length Human CD40 Protein, GST-tagged
Cat.No. : | CD40-3237HF |
Product Overview : | Human CD40 full-length ORF (AAH12419.1) recombinant protein without tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014] |
Source : | In Vitro Cell Free System |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 30.6 kDa |
Protein Length : | 393 amino acids |
AA Sequence : | MVRLPLQCVLWGCLLTAVHPEPPTA CREKQYLINSQCCSLCQPGQKLVSD CTEFTETECLPCGESEFLDTWNRET HCHQHKYCDPNLGLRVQQKGTSETD TICTCEEGWHCTSEACESCVLHRSC SPGFGVKQIATGVSDTICEPCPVGF FSNVSSAFEKCHPWTSCETKDLVVQ QAGTNKTDVVCGPQDRLRALVVIPI IFGILFAILLVLVFIKKVAKKPTNK APHPKQEPQEINFPDDLPGSNTAAP VQETLHGCQPVTQEDGKESRISVQE RQ |
Applications : | Antibody Production Functional Study Compound Screening |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Gene Name : | CD40 CD40 molecule, TNF receptor superfamily member 5 [ Homo sapiens ] |
Official Symbol : | CD40 |
Synonyms : | CD40; CD40 molecule, TNF receptor superfamily member 5; TNFRSF5, tumor necrosis factor receptor superfamily, member 5; tumor necrosis factor receptor superfamily member 5; Bp50; p50; CD40L receptor; CD40 type II isoform; B cell-associated molecule; B cell surface antigen CD40; B-cell surface antigen CD40; CD40 antigen (TNF receptor superfamily member 5); tumor necrosis factor receptor superfamily, member 5; nerve growth factor receptor-related B-lymphocyte activation molecule; CDW40; TNFRSF5; MGC9013; |
Gene ID : | 958 |
mRNA Refseq : | NM_001250 |
Protein Refseq : | NP_001241 |
MIM : | 109535 |
UniProt ID : | P25942 |
Products Types
◆ Recombinant Protein | ||
CD40-1038C | Recombinant Canine CD40 protein(Met1-Ala194) | +Inquiry |
CD40-0811H | Recombinant Human CD40 Protein, His-Flag-StrepII-Tagged | +Inquiry |
CD40-628H | Recombinant Human CD40 Protein | +Inquiry |
CD40-1088M | Recombinant Mouse CD40 Protein (Met1-Arg193), HlgG1 Fc-tagged | +Inquiry |
Cd40-8727R | Recombinant Rat Cd40 protein(Met1-Arg193), His-tagged | +Inquiry |
◆ Lysates | ||
CD40-1254CCL | Recombinant Cynomolgus CD40 cell lysate | +Inquiry |
CD40-1831MCL | Recombinant Mouse CD40 cell lysate | +Inquiry |
CD40-2617HCL | Recombinant Human CD40 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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