Recombinant Full Length Human CHUK Protein, His tagged

• Cat.No.: CHUK-13HFL
• Product Overview: Purified recombinant protein of Human conserved helix-loop-helix ubiquitous kinase (CHUK), full length, with N-terminal His tag, expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-745 aa
• Description: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
• Form: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Molecular Mass: 84.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80 centigrade. Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Concentration: > 0.05 μg/μL as determined by microplate BCA method

Gene Information

• Gene Name: CHUK component of inhibitor of nuclear factor kappa B kinase complex [ Homo sapiens (human) ]
• Official Symbol: CHUK
• Synonyms: CHUK; component of inhibitor of nuclear factor kappa B kinase complex; BPS2; IKK1; IKKA; IKBKA; IKK-1; TCF16; NFKBIKA; IKK-alpha; inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase 1; I-kappa-B kinase-alpha; IKK-a kinase; IkB kinase alpha subunit; Nuclear factor NFkappaB inhibitor kinase alpha; conserved helix-loop-helix ubiquitous kinase; transcription factor 16; EC 2.7.11.10
• Gene ID: 1147
• mRNA Refseq: NM_001278
• Protein Refseq: NP_001269
• MIM: 600664
• UniProt ID: O14666