Human CHUK Knockdown Cell Lysate

Cat.No. : CHUK-111HKCL
Product Overview : WB-validated CHUK Knockdown HeLa Cell Lysate
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Species : Human
Source : HeLa
Tag : Non
Description : This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Form : Cell-Tissue Lysis buffer
Molecular Mass : 85 kDa
Notes : Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
Storage : Store at -20 centigrade for two years.
Concentration : Lot-specific
Shipping : Blue Ice
Components : 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg CHUK KD HeLa cell lysate
Protein Families : Druggable Genome, Protein Kinase
Protein Pathways : Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, MAPK signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway
Lysate QC : RT-qPCR; Western Blotting (WB)
Gene Name CHUK conserved helix-loop-helix ubiquitous kinase [ Homo sapiens (human) ]
Official Symbol CHUK
Synonyms CHUK; conserved helix-loop-helix ubiquitous kinase; TCF16; inhibitor of nuclear factor kappa-B kinase subunit alpha; IkBKA; IKK alpha; IKK1; IKKA; NFKBIKA; TCF-16; IKK-a kinase; I-kappa-B kinase 1; I-kappa-B kinase-alpha; transcription factor 16; IkB kinase alpha subunit; Nuclear factor NFkappaB inhibitor kinase alpha; IKBKA; IKK-alpha;
Gene ID 1147
mRNA Refseq NM_001278
Protein Refseq NP_001269
MIM 600664
UniProt ID O15111

Not For Human Consumption!

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