Recombinant Full Length Human CLEC4E Protein, C-Flag-tagged

• Cat.No.: CLEC4E-679HFL
• Product Overview: Recombinant Full Length Human CLEC4E Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 24.9 kDa
• AA Sequence: MNSSKSSETQCTERGCFSSQMFLWT VAGIPILFLSACFITRCVVTFRIFQ TCDEKKFQLPENFTELSCYN YGSGSVKNCCPLNWEYFQSSCYFFS TDTISWALSLKNCSAMGAHLVVINS QEEQEFLSYKKPKMREFFIG LSDQVVEGQWQWVDGTPLTKSLSFW DVGEPNNIATLEDCATMRDSSNPRQ NWNDVTCFLNYFRICEMVGI
  NPLNKGKSLTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: CLEC4E C-type lectin domain family 4 member E [ Homo sapiens (human) ]
• Official Symbol: CLEC4E
• Synonyms: MINCLE; CLECSF9
• Gene ID: 26253
• mRNA Refseq: NM_014358.4
• Protein Refseq: NP_055173.1
• MIM: 609962
• UniProt ID: Q9ULY5