Recombinant Full Length Human EPHA2 Protein, C-Flag-tagged

• Cat.No.: EPHA2-698HFL
• Product Overview: Recombinant Full Length Human EPHA2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 108.1 kDa
• AA Sequence: MELQAARACFALLWGCALAAAAAAQ GKEVVLLDFAAAGGELGWLTHPYGK GWDLMQNIMNDMPIYMYSVC NVMSGDQDNWLRTNWVYRGEAERIF IELKFTVRDCNSFPGGASSCKETFN LYYAESDLDYGTNFQKRLFT KIDTIAPDEITVSSDFEARHVKLNV EERSVGPLTRKGFYLAFQDIGACVA LLSVRVYYKKCPELLQGLAH FPETIAGSDAPSLATVAGTCVDHAV VPPGGEEPRMHCAVDGEWLVPIGQC LCQAGYEKVEDACQACSPGF FKFEASESPCLECPEHTLPSPEGAT SCECEEGFFRAPQDPASMPCTRPPS APHYLTAVGMGAKVELRWTP PQDSGGREDIVYSVTCEQCWPESGE CGPCEASVRYSEPPHGLTRTSVTVS DLEPHMNYTFTVEARNGVSG LVTSRSFRTASVSINQTEPPKVRLE GRSTTSLSVSWSIPPPQQSRVWKYE VTYRKKGDSNSYNVRRTEGF SVTLDDLAPDTTYLVQVQALTQEGQ GAGSKVHEFQTLSPEGSGNLAVIGG VAVGVVLLLVLAGVGFFIHR RRKNQRARQSPEDVYFSKSEQLKPL KTYVDPHTYEDPNQAVLKFTTEIHP SCVTRQKVIGAGEFGEVYKG MLKTSSGKKEVPVAIKTLKAGYTEK QRVDFLGEAGIMGQFSHHNIIRLEG VISKYKPMMIITEYMENGAL DKFLREKDGEFSVLQLVGMLRGIAA GMKYLANMNYVHRDLAARNILVNSN LVCKVSDFGLSRVLEDDPEA TYTTSGGKIPIRWTAPEAISYRKFT SASDVWSFGIVMWEVMTYGERPYWE LSNHEVMKAINDGFRLPTPM DCPSAIYQLMMQCWQQERARRPKFA DIVSILDKLIRAPDSLKTLADFDPR VSIRLPSTSGSEGVPFRTVS EWLESIKMQQYTEHFMAAGYTAIEK VVQMTNDDIKRIGVRLPGHQKRIAY SLLGLKDQVNTVGIPITRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance

Gene Information

• Gene Name: EPHA2 EPH receptor A2 [ Homo sapiens (human) ]
• Official Symbol: EPHA2
• Synonyms: ECK; CTPA; ARCC2; CTPP1; CTRCT6
• Gene ID: 1969
• mRNA Refseq: NM_004431.5
• Protein Refseq: NP_004422.2
• MIM: 176946
• UniProt ID: P29317