Recombinant Full Length Human GABBR1 Protein, GST-tagged

Cat.No. : GABBR1-5162HF
Product Overview : Human GABBR1 full-length ORF ( NP_068703.1, 1 a.a. - 844 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 121.5 kDa
Protein Length : 844 amino acids
AA Sequence : MGPGAPFARVGWPLPLLVVMAAGVA PVWASHSPHLPRPHSRVPPHPSSER RAVYIGALFPMSGGWPGGQACQPAV EMALEDVNSRRDILPDYELKLIHHD SKCDPGQATKYLYELLYNDPIKIIL MPGCSSVSTLVAEAARMWNLIVLSY GSSSPALSNRQRFPTFFRTHPSATL HNPTRVKLFEKWGWKKIATIQQTTE VFTSTLDDLEERVKEAGIEITFRQS FFSDPAVPVKNLKRQDARIIVGLFY ETEARKVFCEVYKERLFGKKYVWFL IGWYADNWFKIYDPSINCTVDEMTE AVEGHITTEIVMLNPANTRSISNMT SQEFVEKLTKRLKRHPEETGGFQEA PLAYDAIWALALALNKTSGGGGRSG VRLEDFNYNNQTITDQIYRAMNSSS FEGVSGHVVFDASGSRMAWTLIEQL QGGSYKKIGYYDSTKDDLSWSKTDK WIGGSPPADQTLVIKTFRFLSQKLF ISVSVLSSLGIVLAVVCLSFNIYNS HVRYIQNSQPNLNNLTAVGCSLALA AVFPLGLDGYHIGRNQFPFVCQARL WLLGLGFSLGYGSMFTKIWWVHTVF TKKEEKKEWRKTLEPWKLYATVGLL VGMDVLTLAIWQIVDPLHRTIETFA KEEPKEDIDVSILPQLEHCSSRKMN TWLGIFYGYKGLLLLLGIFLAYETK SVSTEKINDHRAVGMAIYNVAVLCL ITAPVTMILSSQQDAAFAFASLAIV FSSYITLVVLFVPKMRRLITRGEWQ SEAQDTMKTGSSTNNNEEEKSRLLE KENRELEKIIAEKEERVSELRHQLQ SRQQLRSRRHPPTPPEPSGGLPRGP PEPPDRLSCDGSRVHLLYK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 [ Homo sapiens ]
Official Symbol : GABBR1
Synonyms : GABBR1; gamma-aminobutyric acid (GABA) B receptor, 1; gamma-aminobutyric acid type B receptor subunit 1; GABA B receptor; GPRC3A; hGB1a; GABA-BR1; GABAB, subunit 1c; seven transmembrane helix receptor; GB1; GABABR1; GABBR1-3; dJ271M21.1.1; dJ271M21.1.2; FLJ92613;
Gene ID : 2550
mRNA Refseq : NM_001470
Protein Refseq : NP_001461
MIM : 603540
UniProt ID : Q9UBS5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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