Recombinant Full Length Human GPI Protein, C-Flag-tagged
Cat.No. : | GPI-621HFL |
Product Overview : | Recombinant Full Length Human GPI Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 63 kDa |
AA Sequence : | MAALTRDPQFQKLQQWYREHRSELN LRRLFDANKDRFNHFSLTLNTNHGH ILVDYSKNLVTEDVMRMLVD LAKSRGVEAARERMFNGEKINYTEG RAVLHVALRNRSNTPILVDGKDVMP EVNKVLDKMKSFCQRVRSGD WKGYTGKTITDVINIGIGGSDLGPL MVTEALKPYSSGGPRVWYVSNIDGT HIAKTLAQLNPESSLFIIAS KTFTTQETITNAETAKEWFLQAAKD PSAVAKHFVALSTNTTKVKEFGIDP QNMFEFWDWVGGRYSLWSAI GLSIALHVGFDNFEQLLSGAHWMDQ HFRTTPLEKNAPVLLALLGIWYINC FGCETHAMLPYDQYLHRFAA YFQQGDMESNGKYITKSGTRVDHQT GPIVWGEPGTNGQHAFYQLIHQGTK MIPCDFLIPVQTQHPIRKGL HHKILLANFLAQTEALMRGKSTEEA RKELQAAGKSPEDLERLLPHKVFEG NRPTNSIVFTKLTPFMLGAL VAMYEHKIFVQGIIWDINSFDQWGV ELGKQLAKKIEPELDGSAQVTSHDA STNGLINFIKQQREARVQTRTRPLE QKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Amino sugar and nucleotide sugar metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway, Starch and sucrose metabolism |
Gene Name : | GPI glucose-6-phosphate isomerase [ Homo sapiens (human) ] |
Official Symbol : | GPI |
Synonyms : | AMF; NLK; PGI; PHI; GNPI; SA36; SA-36 |
Gene ID : | 2821 |
mRNA Refseq : | NM_000175.5 |
Protein Refseq : | NP_000166.2 |
MIM : | 172400 |
UniProt ID : | P06744 |
Products Types
◆ Recombinant Protein | ||
GPI-009H | Recombinant Human GPI Protein, His-tagged | +Inquiry |
GPI-2883H | Recombinant Human Full length GPI protein(1-558 aa), C-His-tagged | +Inquiry |
GPI-1010H | Recombinant Human GPI Protein, His (Fc)-Avi-tagged | +Inquiry |
GPI-2294R | Recombinant Rat GPI Protein, His (Fc)-Avi-tagged | +Inquiry |
GPI-2091M | Recombinant Mouse GPI Protein (2-558 aa), His-B2M-tagged | +Inquiry |
◆ Lysates | ||
GPI-5806HCL | Recombinant Human GPI 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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