Recombinant Full Length Human GSTO1 Protein, C-Flag-tagged

• Cat.No.: GSTO1-1351HFL
• Product Overview: Recombinant Full Length Human GSTO1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 27.4 kDa
• AA Sequence: MSGESARSLGKGSAPPGPVPEGSIR IYSMRFCPFAERTRLVLKAKGIRHE VININLKNKPEWFFKKNPFG LVPVLENSQGQLIYESAITCEYLDE AYPGKKLLPDDPYEKACQKMILELF SKVPSLVGSFIRSQNKEDYA GLKEEFRKEFTKLEEVLTNKKTTFF GGNSISMIDYLIWPWFERLEAMKLN ECVDHTPKLKLWMAAMKEDP
  TVSALLTSEKDWQGFLELYLQNSPE ACDYGLSGPTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450

Gene Information

• Gene Name: GSTO1 glutathione S-transferase omega 1 [ Homo sapiens (human) ]
• Official Symbol: GSTO1
• Synonyms: P28; SPG-R; GSTO 1-1; GSTTLp28; HEL-S-21
• Gene ID: 9446
• mRNA Refseq: NM_004832.3
• Protein Refseq: NP_004823.1
• MIM: 605482
• UniProt ID: P78417