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Recombinant Full Length Human Interleukin-12 Receptor Subunit Beta-1(Il12Rb1) Protein, His-Tagged

Cat.No. : RFL3414HF
Product Overview : Recombinant Full Length Human Interleukin-12 receptor subunit beta-1(IL12RB1) Protein (P42701) (24-662aa), fused to N-terminal His tag, was expressed in E. coli.
  • Specification
  • Gene Information
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Source : E.coli expression system
Species : Homo sapiens (Human)
Tag : His
Form : Lyophilized powder
Protein length : Full Length of Mature Protein (24-662)
AA Sequence : CRTSECCFQDPPYPDADSGSASGPR DLRCYRISSDRYECSWQYEGPTAGV SHFLRCCLSSGRCCYFAAGSATRLQ FSDQAGVSVLYTVTLWVESWARNQT EKSPEVTLQLYNSVKYEPPLGDIKV SKLAGQLRMEWETPDNQVGAEVQFR HRTPSSPWKLGDCGPQDDDTESCLC PLEMNVAQEFQLRRRQLGSQGSSWS KWSSPVCVPPENPPQPQVRFSVEQL GQDGRRRLTLKEQPTQLELPEGCQG LAPGTEVTYRLQLHMLSCPCKAKAT RTLHLGKMPYLSGAAYNVAVISSNQ FGPGLNQTWHIPADTHTEPVALNIS VGTNGTTMYWPARAQSMTYCIEWQP VGQDGGLATCSLTAPQDPDPAGMAT YSWSRESGAMGQEKCYYITIFASAH PEKLTLWSTVLSTYHFGGNASAAGT PHHVSVKNHSLDSVSVDWAPSLLST CPGVLKEYVVRCRDEDSKQVSEHPV QPTETQVTLSGLRAGVAYTVQVRAD TAWLRGVWSQPQRFSIEVQVSDWLI FFASLGSFLSILLVGVLGYLGLNRA ARHLCPPLPTPCASSAIEFPGGKET WQWINPVDFQEEASLQEALVVEMSW DKGERTEPLEKTELPEGAPELALDT ELSLEDGDRCKAKM
Purity : Greater than 90% as determined by SDS-PAGE.
Applications : SDS-PAGE
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Storage Buffer : Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Gene Name : IL12RB1
Synonyms : IL12RB1; IL12R; IL12RB; Interleukin-12 receptor subunit beta-1; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12RB1; IL-12 receptor beta component; CD antigen CD212
UniProt ID : P42701
Gene Name : IL12RB1
Synonyms : IL12RB1; IL12R; IL12RB; Interleukin-12 receptor subunit beta-1; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12RB1; IL-12 receptor beta component; CD antigen CD212
UniProt ID : P42701

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Could you explain the significance of CRISPR/Cas9-mediated gene tagging in tracking IL12RB1 localization? 09/18/2021

Gene tagging allows real-time tracking of IL12RB1 subcellular localization.

Can you elaborate on the use of RNA-seq analysis to profile gene expression changes upon IL12RB1 activation? 07/02/2021

RNA-seq profiles gene expression changes upon IL12RB1 activation.

What are the applications of ChIP-seq in exploring IL12RB1's role in gene regulation? 01/23/2021

ChIP-seq investigates IL12RB1's impact on gene regulation networks.

What methods can be employed to assess IL12RB1 dimerization and its effect on downstream signaling? 06/13/2020

Crosslinking and immunoprecipitation assess IL12RB1 dimerization and signaling.

What techniques are suitable for studying IL12RB1's interaction with IL12A and IL23A? 02/14/2020

Co-immunoprecipitation and ELISA assay IL12RB1 interactions with cytokines.

How can the role of IL12RB1 in signal transduction be elucidated using knockdown experiments? 12/27/2019

Knockdown experiments reveal IL12RB1's contribution to signal transduction.

What are the advantages of using siRNA screening to identify IL12RB1-regulated pathways? 02/22/2019

siRNA screening identifies pathways influenced by IL12RB1 expression.

How do co-crystallization studies aid in understanding the molecular details of IL12RB1 interactions? 01/02/2019

Co-crystallization offers structural insights into IL12RB1 interactions.

How does flow cytometry provide insights into IL12RB1 expression levels on different cell types? 10/26/2018

Flow cytometry quantifies IL12RB1 levels on diverse cell populations.

What experimental approaches validate IL12RB1's involvement in cytokine-mediated immune responses? 06/25/2018

Functional assays validate IL12RB1's role in immune responses.

Customer Reviews (3)

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Reviews
04/06/2022

    Reliable in co-immunoprecipitation.

    10/18/2021

      Effective in asthma models.

      12/21/2017

        great in Western blot analysis.

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