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Recombinant Full Length Human LIF Protein, C-Flag-tagged

Cat.No. : LIF-1814HFL
Product Overview : Recombinant Full Length Human LIF Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 19.7 kDa
AA Sequence : MKVLAAGVVPLLLVLHWKHGAGSPL PITPVNATCAIRHPCHNNLMNQIRS QLAQLNGSANALFILYYTAQ GEPFPNNLDKLCGPNVTDFPPFHAN GTEKAKLVELYRIVVYLGTSLGNIT RDQKILNPSALSLHSKLNAT
ADILRGLLSNVLCRLCSKYHVGHVD VTYGPDTSGKDVFQKKKLGCQLLGK YKQIIAVLAQAFTRTRPLEQKLISE EDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways : Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Gene Name : LIF LIF interleukin 6 family cytokine [ Homo sapiens (human) ]
Official Symbol : LIF
Synonyms : CDF; DIA; HILDA; MLPLI
Gene ID : 3976
mRNA Refseq : NM_002309.5
Protein Refseq : NP_002300.1
MIM : 159540
UniProt ID : P15018

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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