Recombinant Full Length Human P2RX4 Protein, C-Flag-tagged P2RX4-1755HFL

Recombinant Full Length Human P2RX4 Protein, C-Flag-tagged

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Recombinant Full Length Human P2RX4 Protein, C-Flag-tagged

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Cat.No. : P2RX4-1755HFL Optional Service: Optional requirements on this protein
Product Overview : Recombinant Full Length Human P2RX4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
Description : The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 43.2 kDa
AA Sequence : MAGCCAALAA FLFEYDTPRI VLIRSRKVGL MNRAVQLLIL AYVIGWVFVW EKGYQETDSV VSSVTTKVKG VAVTNTSKLG FRIWDVADYV IPAQEENSLF VMTNVILTMN QTQGLCPEIP DATTVCKSDA SCTAGSAGTH SNGVSTGRCV AFNGSVKTCE VAAWCPVEDD THVPQPAFLK AAENFTLLVK NNIWYPKFNF SKRNILPNIT TTYLKSCIYD AKTDPFCPIF RLGKIVENAG HGFQDMAVEG GIMGIQVNWD CNLDRAASLC LPRYSFRRLD TRDVEHNVSP GYNFRFAKYY RDLAGNEQRT LIKAYGIRFD IIVFGKAGKF DIIPTMINIG SGLALLGMAT VLCDIIVLYC MKKRLYYREK KYKYVEDYEQ GLASELDQTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : Druggable Genome, Ion Channels: ATP Receptors, Transmembrane
Protein Pathways : Calcium signaling pathway, Neuroactive ligand-receptor interaction
Figure :

Coomassie blue staining of purified P2RX4 protein.

Gene Name : P2RX4 purinergic receptor P2X 4 [ Homo sapiens (human) ]
Official Symbol : P2RX4
Synonyms : P2X4; P2X4R
Gene ID : 5025
mRNA Refseq : NM_002560.3
Protein Refseq : NP_002551.2
MIM : 600846
UniProt ID : Q99571
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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