Recombinant Full Length Human PRKAA1 Protein, C-Flag-tagged
Cat.No. : | PRKAA1-1007HFL |
Product Overview : | Recombinant Full Length Human PRKAA1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 63.8 kDa |
AA Sequence : | MRRLSSWRKMATAEKQKHDGRVKIG HYILGDTLGVGTFGKVKVGKHELTG HKVAVKILNRQKIRSLDVVG KIRREIQNLKLFRHPHIIKLYQVIS TPSDIFMVMEYVSGGELFDYICKNG RLDEKESRRLFQQILSGVDY CHRHMVVHRDLKPENVLLDAHMNAK IADFGLSNMMSDGEFLRTSCGSPNY AAPEVISGRLYAGPEVDIWS SGVILYALLCGTLPFDDDHVPTLFK KICDGIFYTPQYLNPSVISLLKHML QVDPMKRATIKDIREHEWFK QDLPKYLFPEDPSYSSTMIDDEALK EVCEKFECSEEEVLSCLYNRNHQDP LAVAYHLIIDNRRIMNEAKD FYLATSPPDSFLDDHHLTRPHPERV PFLVAETPRARHTLDELNPQKSKHQ GVRKAKWHLGIRSQSRPNDI MAEVCRAIKQLDYEWKVVNPYYLRV RRKNPVTSTYSKMSLQLYQVDSRTY LLDFRSIDDEITEAKSGTAT PQRSGSVSNYRSCQRSDSDAEAQGK SSEVSLTSSVTSLDSSPVDLTPRPG SHTIEFFEMCANLIKILAQTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Protein Kinase |
Protein Pathways : | Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway, mTOR signaling pathway, Regulation of autophagy |
Gene Name : | PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 [ Homo sapiens (human) ] |
Official Symbol : | PRKAA1 |
Synonyms : | AMPK; AMPKa1; AMPK alpha 1 |
Gene ID : | 5562 |
mRNA Refseq : | NM_006251.6 |
Protein Refseq : | NP_006242.5 |
MIM : | 602739 |
UniProt ID : | Q13131 |
Products Types
◆ Recombinant Protein | ||
PRKAA1-4327R | Recombinant Rat PRKAA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRKAA1-06H | Recombinant Human PRKAA1 complex Protein, N-Flag-tagged | +Inquiry |
PRKAA1-1762H | Recombinant Human PRKAA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRKAA1-007H | Active Recombinant Human PRKAA1 Protein, His-tagged | +Inquiry |
PRKAA1-01H | Recombinant Human PRKAA1 Protein (K45R) | +Inquiry |
◆ Lysates | ||
PRKAA1-1412HCL | Recombinant Human PRKAA1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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