Recombinant Full Length Human Tgf-Beta Receptor Type-2(Tgfbr2) Protein, His-Tagged

Cat.No. : RFL14015HF
Product Overview : Recombinant Full Length Human TGF-beta receptor type-2(TGFBR2) Protein (P37173) (23-567aa), fused to N-terminal His tag, was expressed in E. coli.
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Source : E.coli expression system
Species : Homo sapiens (Human)
Tag : His
Form : Lyophilized powder
Protein length : Full Length of Mature Protein (23-567)
AA Sequence : TIPPHVQKSVNNDMIVTDNNGAVKF PQLCKFCDVRFSTCDNQKSCMSNCS ITSICEKPQEVCVAVWRKNDENITL ETVCHDPKLPYHDFILEDAASPKCI MKEKKKPGETFFMCSCSSDECNDNI IFSEEYNTSNPDLLLVIFQVTGISL LPPLGVAISVIIIFYCYRVNRQQKL SSTWETGKTRKLMEFSEHCAIILED DRSDISSTCANNINHNTELLPIELD TLVGKGRFAEVYKAKLKQNTSEQFE TVAVKIFPYEEYASWKTEKDIFSDI NLKHENILQFLTAEERKTELGKQYW LITAFHAKGNLQEYLTRHVISWEDL RKLGSSLARGIAHLHSDHTPCGRPK MPIVHRDLKSSNILVKNDLTCCLCD FGLSLRLDPTLSVDDLANSGQVGTA RYMAPEVLESRMNLENVESFKQTDV YSMALVLWEMTSRCNAVGEVKDYEP PFGSKVREHPCVESMKDNVLRDRGR PEIPSFWLNHQGIQMVCETLTECWD HDPEARLTAQCVAERFSELEHLDRL SGRSCSEEKIPEDGSLNTTK
Purity : Greater than 90% as determined by SDS-PAGE.
Applications : SDS-PAGE
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Storage Buffer : Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Gene Name : TGFBR2
Synonyms : TGFBR2; TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II
UniProt ID : P37173
Gene Name : TGFBR2
Synonyms : TGFBR2; TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II
UniProt ID : P37173

Not For Human Consumption!

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04/14/2023

    TGFBR2 protein's remarkable performance in ELISA and protein electron microscopy structure analysis positions it as a valuable tool in various fields, including cardiovascular research, developmental biology, and molecular medicine.

    12/13/2022

      TGFBR2 protein's utility extends to protein electron microscopy structure analysis, where it plays a crucial role in investigating the detailed architecture and conformational changes of proteins.

      06/25/2021

        TGFBR2 protein is highly recommended for use in various research applications, including ELISA and protein electron microscopy structure analysis.

        Q&As (5)

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        How is TGFBR2 linked to autoimmune diseases? 04/26/2023

        Dysregulation of TGF-beta signaling, including TGFBR2, has been associated with autoimmune diseases. Understanding these pathways may provide insights into developing targeted therapies.

        Are there clinical trials targeting TGFBR2? 01/12/2020

        Yes, there are ongoing clinical trials exploring the modulation of TGFBR2 for various conditions, including cancer and fibrotic diseases.

        How does TGFBR2 affect cardiovascular health? 12/13/2019

        TGFBR2 is involved in cardiovascular development and homeostasis. Dysregulation can contribute to conditions like aortic aneurysms and other cardiovascular diseases.

        Is TGFBR2 involved in neurological disorders? 01/14/2019

        Some studies suggest a potential link between TGFBR2 and neurological disorders. Further research is ongoing to understand its role in conditions like Alzheimer's and Parkinson's disease.

        Can TGFBR2 be a therapeutic target for fibrotic diseases? 01/19/2018

        Yes, TGFBR2 is implicated in fibrosis, and targeting it may offer therapeutic options for diseases characterized by excessive tissue scarring.

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