Recombinant Full Length Human TIGIT Protein, C-Flag-tagged

• Cat.No.: TIGIT-235HFL
• Product Overview: Recombinant Full Length Human TIGIT Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 26.1 kDa
• AA Sequence: MRWCLLLIWAQGLRQAPLASGMMTG TIETTGNISAEKGGSIILQCHLSST TAQVTQVNWEQQDQLLAICN ADLGWHISPSFKDRVAPGPGLGLTL QSLTVNDTGEYFCIYHTYPDGTYTG RIFLEVLESSVAEHGARFQI PLLGAMAATLVVICTAVIVVVALTR KKKALRIHSVEGDLRRKSAGQEEWS PSAPSPPGSCVQAEAAPAGLCGEQR GEDCAELHDYFNVLSYRSLGNCSFF TETG TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane

Gene Information

• Gene Name: TIGIT T cell immunoreceptor with Ig and ITIM domains [ Homo sapiens (human) ]
• Official Symbol: TIGIT
• Synonyms: VSIG9; VSTM3; WUCAM
• Gene ID: 201633
• mRNA Refseq: NM_173799.4
• Protein Refseq: NP_776160.2
• MIM: 612859
• UniProt ID: Q495A1