Recombinant Human ADAM17 Protein (Met1-Asp563), C-His tagged
Cat.No. : | ADAM17-5123H |
Product Overview : | Recombinant human ADAM17 (Met1-Asp563) fused with the C-terminal His tag was expressed in Mammalian cells. |
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Source : | Mammalian cells |
Species : | Human |
Tag : | His |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 61.93 kDa |
Protein length : | Met1-Asp563 |
Endotoxin : | < 1.0 EU/μg of the protein as determined by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS or lyophilized from PBS. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | ADAM17 ADAM metallopeptidase domain 17 [ Homo sapiens (human) ] |
Official Symbol : | ADAM17 |
Synonyms : | ADAM17; ADAM metallopeptidase domain 17; TACE, tumor necrosis factor, alpha, converting enzyme; disintegrin and metalloproteinase domain-containing protein 17; CD156B; cSVP; TNF-alpha convertase; snake venom-like protease; TNF-alpha converting enzyme; ADAM metallopeptidase domain 18; tumor necrosis factor, alpha, converting enzyme; CSVP; TACE; NISBD; ADAM18; |
Gene ID : | 6868 |
mRNA Refseq : | NM_003183 |
Protein Refseq : | NP_003174 |
MIM : | 603639 |
UniProt ID : | P78536 |
Products Types
◆ Recombinant Protein | ||
ADAM17-073R | Recombinant Rat ADAM17 Protein, His-tagged | +Inquiry |
ADAM17-085M | Recombinant Mouse ADAM17 Protein, His-tagged | +Inquiry |
ADAM17-157R | Recombinant Rat ADAM17 Protein, His (Fc)-Avi-tagged | +Inquiry |
Adam17-308M | Recombinant Mouse Adam17 Protein, His (Fc)-Avi-tagged | +Inquiry |
Adam17-8788R | Active Recombinant Rat Adam17 protein(Met1-Asp563), His-tagged | +Inquiry |
◆ Lysates | ||
ADAM17-1198RCL | Recombinant Rat ADAM17 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0049 | ADAM17 Inhibitor Screening Assay Kit | +Inquiry |
Kit-0048 | ADAM17 fluorometric drug discovery Kit | +Inquiry |
Related Gene
Not For Human Consumption!
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Customer Reviews (3)
Write a reviewCheap price, high quality products, worth buying again
The high quality of the purchased protein helped me to obtain satisfactory experimental results.
Good after-sales service attitude, helped me solve a lot of problems in the experiment.
Q&As (10)
Ask a questionADAM17 is a negative regulator of the RAS system.
Yes, we have produced ADAM17 protein of this purity.
ADAM17 protein can cleave IL6R, TNFR1, ACE2, etc.
ADAM17 is widely expressed in somatic and immune cells
ADAM17 is also currently being used in studies of breast cancer and gastric cancer, etc.
ADAM17 is an activator that mediates the EGFR-PI3K-AKT pathway.
The product manual will contain relevant content on product handling, and you can also consult our technical experts on related issues.
Yes, ADAM17 protein is involved in this promotion.
ADAM17 acts as an activator of Notch pathway by mediating the of cleavage of Notch.
Addition of His tags usually does not affect the function, properties of the target protein.
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