Recombinant Human AHR, His-tagged

• Cat.No.: AHR-9497H
• Product Overview: Recombinant Human AHR protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-387a.a.
• Description: This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: AHR aryl hydrocarbon receptor [ Homo sapiens ]
• Official Symbol: AHR
• Synonyms: AHR; aryl hydrocarbon receptor; bHLHe76; AH-receptor; ah receptor; aromatic hydrocarbon receptor; class E basic helix-loop-helix protein 76
• Gene ID: 196
• mRNA Refseq: NM_001621
• Protein Refseq: NP_001612
• MIM: 600253
• UniProt ID: P35869
• Chromosome Location: 7p15
• Pathway: Adipogenesis, organism-specific biosystem
• Function: DNA binding; DNA binding; Hsp90 protein binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; protein binding; protein dimerization activity; protein heterodimerization activity; receptor activity; sequen