Recombinant Human AHRR Protein, GST-tagged

• Cat.No.: AHRR-465H
• Product Overview: Human AHRR full-length ORF ( AAI60162.1, 1 a.a. - 719 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 79.1 kDa
• AA Sequence: MPRTMIPPGECTYAGRKRRRPLQKQ RPAVGAEKSNPSKRHRDRLNAELDH LASLLPFPPDIISKLDKLSVLRLSV SYLRVKSFFQVVQEQSSRQPAAGAP SPGDSCPLAGSAVLEGRLLLESLNG FALVVSAEGTIFYASATIVDYLGFH QTDVMHQNIYDYIHVDDRQDFCRQL HWAMDPPQVVFGQPPPLETGDDAIL GRLLRAQEWGTGTPTEYSAFLTRCF ICRVRCLLDSTSGFLARGSQAWQLR LCCPEPLMTMQFQGKLKFLFGQKKK APSGAMLPPRLSLFCIAAPVLLPSA AEMKMRSALLRAKPRADTAATADAK VKATTSLCESELHGKPNYSAGRSSR ESGVLVLREQTDAGRWAQVPARAPC LCLRGGPDLVLDPKGGSGDREEEQH RMLSRASGVTGRRETPGPTKPLPWT AGKHSEDGARPRLQPSKNDPPSLRP MPRGSCLPCPCVQGTFRNSPISHPP SPSPSAYSSRTSRPMRDVGEDQVHP PLCHFPQRSLQHQLPQPGAQRFATR GYPMEDMKLQGVPMPPGDLCGPTLL LDVSIKMEKDSGCEGAADGCVPSQV WLGASDRSHPATFPTRMHLKTEPDS RQQVYISHLGHGVRGAQPHGRATAG RSRELTPFHPAHCACLEPTDGLPQS EPPHQLCARGRGEQSCTCRAAEAAP VVKREPLDSPQWATHSQGMVPGMLP KSALATLVPPQASGCTFLP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AHRR aryl-hydrocarbon receptor repressor [ Homo sapiens ]
• Official Symbol: AHRR
• Synonyms: AHRR; aryl-hydrocarbon receptor repressor; AHH, AHHR, aryl hydrocarbon receptor regulator; aryl hydrocarbon receptor repressor; bHLHe77; KIAA1234; ahR repressor; dioxin receptor repressor; aryl hydrocarbon hydroxylase regulator; class E basic helix-loop-helix protein 77; AHH; AHHR; MGC167813; MGC176630
• Gene ID: 57491
• mRNA Refseq: NM_001242412
• Protein Refseq: NP_001229341
• MIM: 606517
• UniProt ID: A9YTQ3