Recombinant Human ANAPC15 Protein (1-121 aa), GST-tagged

• Cat.No.: ANAPC15-366H
• Product Overview: Recombinant Human ANAPC15 Protein (1-121 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Cell Biology. Protein Description: Full Length.

Specification

• Description: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assbly checkpoint. Also required for degradation of CDC20.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 41.3 kDa
• Protein length: 1-121 aa
• AA Sequence: MSTLFPSLFPRVTETLWFNLDRPCV EETELQQQEQQHQAWLQSIAEKDNN LVPIGKPASEHYDDEEEEDDEDDED SEEDSEDDEDMQDMDEMNDYNESPD DGEVNEVDMEGNEQDQDQWMI
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: ANAPC15 anaphase promoting complex subunit 15 [ Homo sapiens ]
• Official Symbol: ANAPC15
• Synonyms: APC15; HSPC020; C11orf51
• Gene ID: 25906
• mRNA Refseq: NM_014042.2
• Protein Refseq: NP_054761.1
• MIM: 614717
• UniProt ID: P60006