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Recombinant Human ARHGAP22 Protein, MYC/DDK-tagged

Cat.No. : ARHGAP22-2588H
Product Overview : Recombinant Human ARHGAP22 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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  • Gene Information
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Description : This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 76.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ARHGAP22 Rho GTPase activating protein 22 [ Homo sapiens ]
Official Symbol : ARHGAP22
Synonyms : RhoGAP2; RhoGap22
Gene ID : 58504
mRNA Refseq : NM_001256024
Protein Refseq : NP_001242953
MIM : 610585
UniProt ID : Q7Z5H3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (9)

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What are the potential signaling pathways influenced by ARHGAP22? 01/22/2023

The exact signaling pathways influenced by ARHGAP22 are still largely unknown. Since it is predicted to possess a RhoGAP domain, it suggests a potential involvement in modulating Rho GTPase-mediated signaling networks, which are crucial for numerous cellular processes ranging from cell migration to cytoskeletal organization.

Are there any known interacting partners of ARHGAP22? 05/19/2022

The protein interaction network of ARHGAP22 is not well-defined. However, it has been reported to potentially interact with the Rho GTPase Cdc42, suggesting a role in regulating Cdc42-mediated signaling pathways.

How does ARHGAP22 expression change under different physiological or pathological conditions? 10/22/2020

The regulation of ARHGAP22 expression under different conditions has not been extensively examined. It is necessary to explore its expression patterns in various physiological and pathological contexts to determine if it is influenced by specific cues or stimuli.

Is ARHGAP22 associated with cancer? 08/23/2020

There is limited evidence regarding the association between ARHGAP22 and cancer. While some studies have identified alterations in ARHGAP22 expression in certain cancer types, the functional implications and clinical significance are still unclear and require further investigation.

Can ARHGAP22 be targeted for therapeutic purposes? 01/30/2019

The therapeutic potential of targeting ARHGAP22 is not yet explored or well-understood due to limited research on its function. Further investigation into its role in cellular processes and disease pathogenesis is necessary before any targeted therapeutic strategies can be considered.

Are there any animal models available to study ARHGAP22 function? 01/27/2019

Currently, there are no specific animal models available to study ARHGAP22 function. Generating animal models, such as knockout mice or zebrafish models, could be valuable in investigating its in vivo role and understanding its significance in biological processes.

Are there any post-translational modifications of ARHGAP22? 06/22/2018

Limited information is available regarding post-translational modifications of ARHGAP22, as research on this protein is relatively scarce. Further studies are needed to explore any potential modifications and their functional consequences.

Is ARHGAP22 associated with any genetic disorders? 11/14/2016

As of now, there are no known genetic disorders specifically linked to ARHGAP22 mutations or dysregulation. However, considering its potential role in cellular processes, it is plausible that future studies may unveil associations between ARHGAP22 variations and certain diseases or disorders.

Is ARHGAP22 expressed in specific tissues or cell types? 09/07/2016

While the specific tissue or cell type expression patterns of ARHGAP22 have not been extensively studied, existing data suggests that it is expressed in a wide range of tissues, including the brain, skeletal muscle, heart, liver, and kidneys.

Customer Reviews (8)

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Reviews
12/08/2021

    ARHGAP22 protein is an enzyme involved in the digestion of carbohydrates, specifically starch.

    09/17/2021

      A reliable manufacturer ensures the production and purification of ARHGAP22 protein, maintaining its quality and purity.

      01/05/2020

        Manufacturers can actively seek collaborations and partnerships with researchers to develop new applications or optimize methodologies using ARHGAP22 protein.

        06/22/2018

          the manufacturer's dedication to continuous improvement and innovation is evident in their ongoing efforts to enhance the ARHGAP22 protein's performance and optimize its applications.

          11/14/2016

            This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.

            10/22/2016

              Manufacturers should provide detailed information about the production process, quality control measures, and purity assessment methods employed.

              10/10/2016

                Its purity and consistency guarantee accurate and consistent results, allowing for confident data interpretation and analysis.

                06/02/2016

                  The exceptional quality and reliability of the ARHGAP22 protein provided by the manufacturer cannot be overstated.

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