Recombinant Human ARHGDIB Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ARHGDIB-3480H
• Product Overview: ARHGDIB MS Standard C13 and N15-labeled recombinant protein (NP_001166) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 23 kDa
• AA Sequence: MTEKAPEPHVEEDDDDELDSKLNYK PPPQKSLKELQEMDKDDESLIKYKK TLLGDGPVVTDPKAPNVVVTRLTLV CESAPGPITMDLTGDLEALKKETIV LKEGSEYRVKIHFKVNRDIVSGLKY VQHTYRTGVKVDKATFMVGSYGPRP EEYEFLTPVEEAPKGMLARGTYHNK SFFTDDDKQDHLSWEWNLSIKKEWT ETRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ARHGDIB Rho GDP dissociation inhibitor beta [ Homo sapiens (human) ]
• Official Symbol: ARHGDIB
• Synonyms: ARHGDIB; Rho GDP dissociation inhibitor (GDI) beta; GDIA2, GDID4, RAP1GN1; rho GDP-dissociation inhibitor 2; Ly GDI; RhoGDI2; Rho GDI 2; rho-GDI beta; D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1
• Gene ID: 397
• mRNA Refseq: NM_001175
• Protein Refseq: NP_001166
• MIM: 602843
• UniProt ID: P52566