Recombinant Human ATIC protein, His-tagged


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Recombinant Human ATIC protein, His-tagged

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Cat.No. : ATIC-24H
Product Overview : Recombinant Human ATIC, fused with N-His tag, was expressed in E. coli.
Description : Bifunctional purine biosynthesis protein PURH is a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity.A mutation in this gene results in AICA-ribosiduria.
Source : E.coli
Species : Human
Tag : His
Form : 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
Molecular Mass : 66.5kDa(including fusion tag)
Protein length : 607aa(including fusion tag)
Applications : WB, ELISA, IP, antibody production, protein array
Storage : Store at -80°C and avoid repeated freeze-thaw cycles.
Gene Name : ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [ Homo sapiens ]
Official Symbol : ATIC
Gene ID : 471
mRNA Refseq : NM_004044
Protein Refseq : NP_004035
MIM : 601731
UniProt ID : P31939
Chromosome Location : Inosine monophosphate biosynthesis, PRPP + glutamine =>IMP, organism-specific biosystem; Inosine monophosphate biosynthesis, PRPP + glutamine => IMP, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem;
Pathway : IMP cyclohydrolase activity; hydrolase activity; phosphoribosylaminoimidazolecarboxamide formyltransferase activity; protein homodimerization activity; transferase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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