Recombinant Human ATOH1 protein

• Cat.No.: ATOH1-369H
• Product Overview: Recombinant Human ATOH1(158-354aa) was expressed in E. coli.

Specification

• Description: ATOH1, also known as protein atonal homolog 1, activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. This protein may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.
• Source: E. coli
• Species: Human
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.4M urea
• Molecular Mass: 21.3 kDa
• AA Sequence: MKQRRLAANA RERRRMHGLN HAFDQLRNVI PSFNNDKKLS KYETLQMAQI YINALSELLQ TPSGGEQPPP PPASCKSDHH HLRTAASYEGGAGNATAAGA QQASGGSQRP TPPGSCRTRF SAPASAGGYS VQLDALHFST FEDSALTAMM AQKNLSPSLP GSILQPVQEE NSKTSPRSHRSDGEFSPHSH YSDSDEAS
• Purity: > 85% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ATOH1 atonal homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: ATOH1
• Synonyms: ATOH1; atonal homolog 1 (Drosophila); protein atonal homolog 1; bHLHa14; HATH1; MATH 1; Math1; helix-loop-helix protein hATH-1; class A basic helix-loop-helix protein 14; ATH1; MATH-1
• Gene ID: 474
• mRNA Refseq: NM_005172
• Protein Refseq: NP_005163
• MIM: 601461
• UniProt ID: Q92858
• Chromosome Location: 4q22
• Function: chromatin DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity