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Recombinant Human ATXN7 protein, His&Myc-tagged

Cat.No. : ATXN7-917H
Product Overview : Recombinant Human ATXN7 protein(O15265)(79-401aa), fused with N-terminal His tag and C-terminal Myc tag, was expressed in E. coli.
  • Specification
  • Gene Information
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Source : E. coli
Species : Human
Tag : His&Myc
Form : If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Molecular Mass : 43.1 kDa
Protein length : 79-401aa
AA Sequence : GERRPLPSPEVMLGQSWNLWVEASK LPGKDGTELDESFKEFGKNREVMGL CREDMPIFGFCPAHDDFYLVVCNDC NQVVKPQAFQSHYERRHSSSSKPPL AVPPTSVFSFFPSLSKSKGGSASGS NRSSSGGVLSASSSSSKLLKSPKEK LQLRGNTRPMHPIQQSRVPHGRIMT PSVKVEKIHPKMDGTLLKSAVGPTC PATVSSLVKPGLNCPSIPKPTLPSP GQILNGKGLPAPPTLEKKPEDNSNN RKFLNKRLSEREFDPDIHCGVIDLD TKKPCTRSLTCKTHSLTQRRAVQGR RKRFDVLLAEHKNKTREKELIRH
Purity : Greater than 85% as determined by SDS-PAGE.
Storage : Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Gene Name : ATXN7 ataxin 7 [ Homo sapiens ]
Official Symbol : ATXN7
Synonyms : ATXN7; ataxin 7; SCA7, spinocerebellar ataxia 7 (olivopontocerebellar atrophy with retinal degeneration); ataxin-7; ADCAII; OPCA3; spinocerebellar ataxia type 7 protein; SCA7; FLJ17787;
Gene ID : 6314
mRNA Refseq : NM_000333
Protein Refseq : NP_000324
MIM : 607640
UniProt ID : O15265

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the structural features of ATXN7 protein? 10/22/2022

The ATXN7 protein consists of multiple functional domains, including multiple HEAT repeats, which may be involved in protein interactions and regulation of function.

How about the cellular localization of ATXN7 protein? 07/07/2021

ATXN7 protein is mainly located in the nucleus and participates in the regulation of gene transcription.

What is the regulatory mechanism of ATXN7 protein? 12/06/2019

The expression and function of ATXN7 protein are affected by multiple regulatory mechanisms, including transcriptional regulation, post-translational modification, and protein-protein interaction.

What are the implications of ATXN7 protein research for disease treatment? 10/03/2019

In-depth study of the function and regulatory mechanism of ATXN7 protein will help to reveal the mechanism of spinocerebellar ataxia (SCA7) and provide new targets and strategies for the diagnosis and treatment of the disease.

Which diseases are associated with ATXN7 protein mutations? 08/29/2019

The protein mutations are associated with the development of spinocerebellar ataxia (SCA7).

How does the ATXN7 protein interact with other proteins? 07/02/2019

ATXN7 protein interacts with multiple proteins, including transcription factors, coactivators, and other regulatory proteins.

Customer Reviews (3)

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Reviews
04/26/2022

    Because the extraordinary stability of ATXN7 under various conditions highlights its robustness and versatility.

    02/03/2021

      Application range of ATXN7 is really wide, from the laboratory to the clinic, can see its figure, it is really rare.

      01/27/2019

        This powerful biological activity of proteins combined with their high purity makes their experimental results extremely reliable, which is of great significance in the field of scientific research.

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