Recombinant Human BAK1 Protein, His tagged

• Cat.No.: BAK1-22H
• Product Overview: Recombinant Human BAK1 Protein, Sourced from E.coli, Pro20-Asn124, with N-terminal His Tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 20-124 aa
• Description: Bcl-2 homologous antagonist killer (BAK) protein is a pro-apoptotic member of the Bcl-2 protein family. In healthy cells, BAK exists in the mitochonidria in an inactive state. Once activated by apoptotic signaling, BAK forms an oligomerized pore in the mitochondrial membrane allowing the release of proapoptotic factors into the cytosol leading to the dismantling of the cell.
• Form: Lyophilized from 1× PBS with Trehalose
• Molecular Mass: 13.9 kDa
• Purity: >99% by SDS-PAGE
• Applications: ELISA and Western Blot Analysis
• Storage: 2 years at -80 centigrade; 2 years at -20 or 4 centigrade Upon reconstitution: 2 years at -80 centigrade; 2 years at -20 centigrade For long-term storage, store for up to 2 years at -20 & -80 centigrade after reconstitution. Expiration is 2 years from date of receipt.
• Shipping: Ambient
• Reconstitution: Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% protein.

Gene Information

• Gene Name: BAK1 BCL2 antagonist/killer 1 [ Homo sapiens (human) ]
• Official Symbol: BAK1
• Synonyms: BAK1; BCL2 antagonist/killer 1; BAK; CDN1; BCL2L7; BAK-LIKE; bcl-2 homologous antagonist/killer; BCL2-like 7 protein; apoptosis regulator BAK; bcl-2-like protein 7; bcl2-L-7; pro-apoptotic protein BAK
• Gene ID: 578
• mRNA Refseq: NM_001188
• Protein Refseq: NP_001179
• MIM: 600516
• UniProt ID: Q16611