Recombinant Full Length Mouse Bcl-2 Homologous Antagonist/Killer(Bak1) Protein, His tagged

• Cat.No.: RFL9990MF
• Product Overview: Recombinant Full Length Mouse Bcl-2 Homologous Antagonist/Killer(Bak1) Protein with His tag was expressed in HEK293.

Specification

• Species: Mouse
• Source: HEK293
• Tag: His
• Description: Enables identical protein binding activity. Involved in cellular response to UV; positive regulation of apoptotic process; and release of cytochrome c from mitochondria. Acts upstream of or within several processes, including apoptotic process involved in blood vessel morphogenesis; apoptotic signaling pathway; and lymphocyte apoptotic process. Located in cytosol; endoplasmic reticulum; and mitochondrial outer membrane. Part of BAK complex. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in ataxia telangiectasia and cervix carcinoma. Orthologous to human BAK1 (BCL2 antagonist/killer 1).
• Form: 25 mM Tris-HCl, 250 mM NaCl and 10% glycerol, pH 7.3
• Molecular Mass: 25.6 kDa
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Stable for at least 1 year from receipt of products under proper storage and handling conditions.
• Concentration: 0.17 mg/mL by Bradford

Gene Information

• Gene Name: Bak1 BCL2-antagonist/killer 1 [ Mus musculus (house mouse) ]
• Official Symbol: Bak1
• Synonyms: BAK1; BCL2-antagonist/killer 1; bcl-2 homologous antagonist/killer; apoptosis regulator BAK; Bcl2 homologous antagonist/killer; Bak; N-Bak; N-BAK1
• Gene ID: 12018
• mRNA Refseq: NM_007523
• Protein Refseq: NP_031549
• UniProt ID: O08734