Recombinant Human CACNA2D1 protein, Trx-His-SUMO-tagged
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Cat.No. : | CACNA2D1-29H |
Product Overview : | Recombinant Human CACNA2D1, fused with Trx-His-SUMO tag, was expressed in E. coli. |
Description : | This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of acomplex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
Source : | E.coli |
Species : | Human |
Tag : | Trx-His-SUMO |
Form : | 20mM Hepes, 50mM NaCl, 1‰ Tween20, pH8.0. |
Molecular Mass : | 148kDa(including fusion tag) |
Protein length : | 1315aa(including fusion tag) |
Applications : | WB, ELISA, IP, antibody production, protein array |
Storage : | Store at -80°C and avoid repeated freeze-thaw cycles. |
Gene Name : | CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 [ Homo sapiens ] |
Official Symbol : | CACNA2D1 |
Synonyms : | CACNA2D1; CACNA2; CCHL2A; CACNL2A; |
Gene ID : | 781 |
mRNA Refseq : | NM_000722 |
Protein Refseq : | NP_000713 |
MIM : | 114204 |
UniProt ID : | P54289 |
Chromosome Location : | Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; |
Pathway : | metal ion binding; contributes_to voltage-gated calcium channel activity; voltage-gated ion channel activity; |
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