Recombinant Human CASP4 Protein, GST-Tagged
Cat.No. : | CASP4-0424H |
Product Overview : | Human CASP4 full-length ORF (AAH17839, 1 a.a. - 377 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 67.21 kDa |
AA Sequence : | MAEGNHRKKPLKVLESLGKDFLTGV LDNLVEQNVLNWKEEEKKKYYDAKT EDKVRVMADSMQEKQRMAGQMLLQT FFNIDQISPNKKAHPNMEAGPPESG ESTDALKLCPHEEFLRLCKERAEEI YPIKERNNRTRLALIICNTEFDHLP PRNGADFDITGMKELLEGLDYSVDV EENLTARDMESALRAFATRPEHKSS DSTFLVLMSHGILEGICGTVHDEKK PDVLLYDTIFQIFNNRNCLSLKDKP KVIIVQACRGANRGELWVRDSPASL EVASSQSSENLEEDAVYKTHVEKDF IAFCSSTPHNVSWRDSTMGSIFITQ LITCFQKYSWCCHLEEVFRKVQQSF ETPRAKAQMPTIERLSMTRYFYLFP GN |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CASP4 caspase 4, apoptosis-related cysteine peptidase [ Homo sapiens ] |
Official Symbol : | CASP4 |
Synonyms : | CASP4; caspase 4, apoptosis-related cysteine peptidase; caspase 4, apoptosis related cysteine protease; caspase-4; ICE(rel)II; ICH 2; TX; CASP-4; ICE(rel)-II; protease TX; protease ICH-2; apoptotic cysteine protease Mih1/TX; caspase 4, apoptosis-related cysteine protease; ICH-2; Mih1/TX; ICEREL-II; |
Gene ID : | 837 |
mRNA Refseq : | NM_001225 |
Protein Refseq : | NP_001216 |
MIM : | 602664 |
UniProt ID : | P49662 |
Products Types
◆ Recombinant Protein | ||
CASP4-2594H | Recombinant Human CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP4-462R | Recombinant Rhesus Macaque CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Casp4-626R | Recombinant Rat Casp4 Protein, His-tagged | +Inquiry |
CASP4-01H | Active Recombinant Human CASP4 Protein | +Inquiry |
CASP4-1244M | Recombinant Mouse CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CASP4-7836HCL | Recombinant Human CASP4 293 Cell Lysate | +Inquiry |
CASP4-7837HCL | Recombinant Human CASP4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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