Recombinant Human CD4 Protein, Fc & Avi-tagged
Cat.No. : | CD4-23H |
Product Overview : | Biotinylated Human CD4, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Pro 396. This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag. The single lysine residue in the Avitag is enzymatically labeled with biotin. |
- Specification
- Gene Information
- Related Products
Description : | T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc & Avi |
Predicted N Terminal : | Lys 26 |
Molecular Mass : | The protein has a calculated MW of 69.7 kDa. As a result of glycosylation, the protein migrates as 80 kDa under reducing (R) condition, and 150 kDa under non-reducing (NR) condition (SDS-PAGE). |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at: 4-8 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as rotectant before lyophilization. |
Gene Name : | CD4 |
Official Symbol : | CD4 CD4 molecule [ Homo sapiens (human) ] |
Synonyms : | CD4; CD4mut; LEU3; CD4 molecule; T-cell surface glycoprotein CD4; CD4 antigen (p55); CD4 receptor; T-cell surface antigen T4/Leu-3 |
Gene ID : | 920 |
mRNA Refseq : | NM_000616 |
Protein Refseq : | NP_000607 |
MIM : | 186940 |
UniProt ID : | P01730 |
Products Types
◆ Recombinant Protein | ||
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Cd4-841M | Recombinant Mouse Cd4 Protein, MYC/DDK-tagged | +Inquiry |
CD4-3F | Recombinant Feline CD4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD4-158R | Recombinant Rhesus macaque CD4 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CD4-1865FCL | Recombinant Ferret CD4 cell lysate | +Inquiry |
CD4-1905HCL | Recombinant Human CD4 cell lysate | +Inquiry |
CD4-2580MCL | Recombinant Mouse CD4 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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