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Recombinant Human CD4 therapeutic protein(Alvircept sudotox)

Cat.No. : CD4-P022H
Product Overview : The therapeutic protein is a form of recombinant CD4 derived from Pneumonas aeruginosa
exotoxin A.
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Description : This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Source : Pneumonas aeruginosa exotoxin A
Species : Human
Endotoxin : < 0.1 EU per μg of the protein
Purity : >97%
Tag : Non
Alias : CD4; CD4mut; Alvircept sudotox
Gene Name : CD4 CD4 molecule [ Homo sapiens ]
Official Symbol : CD4
Synonyms : CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
Gene ID : 920
mRNA Refseq : NM_000616
Protein Refseq : NP_000607
MIM : 186940
UniProt ID : P01730
Chromosome Location : 12p13.31
Pathway : Adaptive Immune System, organism-specific biosystem; Alpha-defensins, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Arf1 pathway, organism-specific biosystem; Binding and entry of HIV virion, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem;
Function : MHC class II protein binding; coreceptor activity; enzyme binding; extracellular matrix structural constituent; glycoprotein binding; protein binding; protein homodimerization activity; protein kinase binding; receptor activity; transmembrane signaling receptor activity; zinc ion binding;

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
01/08/2031

    The CD4 proteins purchased from your company is suitable for ELISA.

    02/06/2023

      Protein products are put into experiments with good effect and reliable experimental results.

      01/22/2022

        The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments.

        Q&As (3)

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        What is the connection between CD4 and glycoprotein GP120? 11/09/2022

        CD4 binds to glycoprotein GP120.

        Where is CD4 primarily expressed? 02/26/2022

        CD4 is mainly expressed in T cells and thymocytes.

        Where is CD4 localized? 03/14/2021

        CD4 is localized in the cell membrane.

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