Recombinant Human CD4 therapeutic protein(Alvircept sudotox)
Cat.No. : | CD4-P022H |
Product Overview : | The therapeutic protein is a form of recombinant CD4 derived from Pneumonas aeruginosa exotoxin A. |
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Description : | This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. |
Source : | Pneumonas aeruginosa exotoxin A |
Species : | Human |
Endotoxin : | < 0.1 EU per μg of the protein |
Purity : | >97% |
Tag : | Non |
Alias : | CD4; CD4mut; Alvircept sudotox |
Gene Name : | CD4 CD4 molecule [ Homo sapiens ] |
Official Symbol : | CD4 |
Synonyms : | CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut; |
Gene ID : | 920 |
mRNA Refseq : | NM_000616 |
Protein Refseq : | NP_000607 |
MIM : | 186940 |
UniProt ID : | P01730 |
Chromosome Location : | 12p13.31 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Alpha-defensins, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Arf1 pathway, organism-specific biosystem; Binding and entry of HIV virion, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; |
Function : | MHC class II protein binding; coreceptor activity; enzyme binding; extracellular matrix structural constituent; glycoprotein binding; protein binding; protein homodimerization activity; protein kinase binding; receptor activity; transmembrane signaling receptor activity; zinc ion binding; |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewThe CD4 proteins purchased from your company is suitable for ELISA.
Protein products are put into experiments with good effect and reliable experimental results.
The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments.
Q&As (3)
Ask a questionCD4 binds to glycoprotein GP120.
CD4 is mainly expressed in T cells and thymocytes.
CD4 is localized in the cell membrane.
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