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Recombinant Human CD46 protein, GST-tagged

Cat.No. : CD46-6463H
Product Overview : Recombinant Human CD46 protein(P15529)(164-325aa), fused with N-terminal GST tag, was expressed in E.coli.
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Source : E.coli
Species : Human
Tag : GST
Protein length : 164-325aa
Form : If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Molecular Mass : 47.0 kDa
AASequence : PPPKIKNGKHTFSEVEVFEYLDAVT YSCDPAPGPDPFSLIGESTIYCGDN SVWSRAAPECKVVKCRFPVVENGKQ ISGFGKKFYYKATVMFECDKGFYLD GSDTIVCDSNSTWDPPVPKCLKVST SSTTKSPASSASGPRPTYKPPVSNY PGYPKPEEGILDKGRIVTDRSASRV SVRT
Purity : Greater than 85% as determined by SDS-PAGE.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.
Gene Name : CD46 CD46 molecule, complement regulatory protein [ Homo sapiens ]
Official Symbol : CD46
Synonyms : CD46; CD46 molecule, complement regulatory protein; antigen identified by monoclonal TRA 2 10 , CD46 antigen, complement regulatory protein , MCP, membrane cofactor protein (CD46, trophoblast lymphocyte cross reactive antigen) , MIC10; membrane cofactor protein; MGC26544; TLX; TRA2.10; measles virus receptor; complement membrane cofactor protein; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; CD46 antigen, complement regulatory protein; trophoblast-lymphocyte cross-reactive antigen; antigen identified by monoclonal TRA-2-10; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); MCP; AHUS2; MIC10;
Gene ID : 4179
mRNA Refseq : NM_002389
Protein Refseq : NP_002380
MIM : 120920
UniProt ID : P15529

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
10/19/2022

    The CD46 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.

    08/09/2019

      With the CD46 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.

      03/05/2019

        Its unique properties make CD46 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.

        Q&As (5)

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        How does CD46 protein interact with other immune system components? 08/20/2021

        CD46 protein interacts with complement regulatory proteins and immune cells to regulate immune responses and maintain homeostasis.

        What are the potential side effects of targeting CD46 protein for therapy? 01/05/2020

        Potential side effects of targeting CD46 protein for therapy may include disturbances in immune regulation and increased susceptibility to infections.

        How does the CD46 protein contribute to immune regulation? 08/11/2018

        CD46 protein regulates the activation of complement system and modulates T cell responses, contributing to immune regulation.

        Can mutations in the CD46 gene lead to genetic disorders? 09/22/2017

        Mutations in the CD46 gene have been associated with genetic disorders such as atypical hemolytic uremic syndrome (aHUS) and other complement-related disorders.

        Is CD46 protein involved in cancer progression or treatment resistance? 08/07/2016

        CD46 protein has been implicated in cancer progression and treatment resistance, particularly in certain types of leukemia and solid tumors.

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