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Recombinant Human CD6 protein, His-tagged

Cat.No. : CD6-018H
Product Overview : Recombinant Human CD6 protein(His 18 - Glu 398) (P30203-1), fused with C-terminal His tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4.
Molecular Mass : The protein has a calculated MW of 42.5 kDa. The protein migrates as 60-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : His 18 - Glu 398
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Storage : This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : CD6 CD6 molecule [ Homo sapiens ]
Official Symbol : CD6
Synonyms : CD6; CD6 molecule; CD6 antigen; T-cell differentiation antigen CD6; Tp120; T12; TP120; FLJ44171;
Gene ID : 923
mRNA Refseq : NM_001254750
Protein Refseq : NP_001241679
MIM : 186720
UniProt ID : P30203

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can you explain the role of CD6 in T-cell co-stimulation and its implications for adaptive immune responses? 02/18/2022

CD6 provides co-stimulatory signals to T cells, influencing their activation and differentiation. This contributes to the regulation of adaptive immune responses.

How are CD6 genes polymorphic, and what is the significance of genetic variations in the context of autoimmune diseases? 07/19/2021

CD6 genes exhibit polymorphisms, and certain variations are associated with susceptibility to autoimmune diseases, indicating a potential role in immune dysregulation.

How does CD6 contribute to the formation of immunological synapses, and what molecular events are involved in this process? 04/01/2020

CD6 is involved in immunological synapse formation, and its interactions with ligands, such as ALCAM, play a role in stabilizing T-cell interactions with antigen-presenting cells.

How does CD6 influence T-cell trafficking and migration, and what are the implications for immune surveillance and inflammation? 09/28/2019

CD6 modulates T-cell trafficking and migration, impacting immune surveillance and inflammation. Its interactions with adhesion molecules contribute to these processes.

What is the relationship between CD6 and antigen-presenting cells, and how does it impact the initiation of immune responses? 11/05/2018

CD6 interacts with antigen-presenting cells, facilitating T-cell activation. This interaction is pivotal for the initiation and regulation of immune responses.

Customer Reviews (3)

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04/05/2021

    Fantastic customer support. They genuinely care about the success of our research.

    11/11/2020

      Quality you can trust. Our lab has seen improved precision since using this product.

      07/27/2019

        Shipping is always on time, and the packaging ensures the product arrives in perfect condition.

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