Active Recombinant Human CHUK Protein, GST-tagged
Cat.No. : | CHUK-5129H |
Product Overview : | Human CHUK (NP_001269.3, 1 a.a. - 745 a.a.) full-length recombinant protein with GST tag expressed in baculovirus infected Sf21 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq |
Source : | Insect Cell |
Species : | Human |
Tag : | GST |
Form : | Liquid |
Bio-activity : | The activity was determined by IMAPTM assay. The enzyme was incubated with fluorescein labeled peptide and phosphorylation was detected by IMAPTM technology (fluorescence polarization). Substrate: I-kappaB-alpha peptide. ATP: 100 μM. |
Molecular Mass : | 111 kDa |
Purity : | 93 % by SDS-PAGE/CBB staining |
Applications : | Functional Study SDS-PAGE |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol) |
Gene Name : | CHUK conserved helix-loop-helix ubiquitous kinase [ Homo sapiens ] |
Official Symbol : | CHUK |
Synonyms : | CHUK; conserved helix-loop-helix ubiquitous kinase; TCF16; inhibitor of nuclear factor kappa-B kinase subunit alpha; IkBKA; IKK alpha; IKK1; IKKA; NFKBIKA; TCF-16; IKK-a kinase; I-kappa-B kinase 1; I-kappa-B kinase-alpha; transcription factor 16; IkB kinase alpha subunit; Nuclear factor NFkappaB inhibitor kinase alpha; IKBKA; IKK-alpha; |
Gene ID : | 1147 |
mRNA Refseq : | NM_001278 |
Protein Refseq : | NP_001269 |
MIM : | 600664 |
UniProt ID : | O15111 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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