Recombinant Human CLC Protein, His-tagged
Cat.No. : | CLC-616H |
Product Overview : | Recombinant Human CLC(Ser2~Arg142) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 17.8kDa |
Protein length : | Ser2~Arg142 |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others |
Gene Name : | CLC Charcot-Leyden crystal protein [ Homo sapiens ] |
Official Symbol : | CLC |
Synonyms : | CLC; Charcot-Leyden crystal protein; eosinophil lysophospholipase; galectin 10; LGALS10; LPPL_HUMAN; lysolecithin acylhydrolase; MGC149659; galectin-10; GAL10; Gal-10; LGALS10A; |
Gene ID : | 1178 |
mRNA Refseq : | NM_001828 |
Protein Refseq : | NP_001819 |
MIM : | 153310 |
UniProt ID : | Q05315 |
Products Types
◆ Recombinant Protein | ||
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CLC-1408H | Recombinant Human CLC Protein, GST-tagged | +Inquiry |
CLC-28114TH | Recombinant Human CLC, His-tagged | +Inquiry |
CLC-11272H | Recombinant Human CLC, GST-tagged | +Inquiry |
CLC-1741H | Recombinant Human CLC Protein (Ser2-Arg142), His tagged | +Inquiry |
◆ Lysates | ||
CLC-7479HCL | Recombinant Human CLC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThere is emerging evidence that CLC proteins may play a role in neurological disorders, making them potential targets for drug development in this field.
CLC proteins are involved in the transport of chloride ions in the kidney, and mutations in CLC genes can lead to renal disorders such as Bartter syndrome.
Modulating the activity of CLC proteins may offer potential therapeutic benefits in the treatment of certain renal disorders by restoring normal chloride ion transport.
There is evidence suggesting that CLC proteins may play a role in pain perception, making them potential targets for the development of novel pain medications.
Several research groups are investigating the potential of targeting CLC proteins for therapeutic intervention in muscle disorders and cystic fibrosis.
Customer Reviews (3)
Write a reviewthe high-quality CLC protein is available in various forms, including recombinant proteins and purified samples, enabling researchers to select the most suitable format for their specific experimental setup.
This enables researchers to confidently incorporate CLC into their studies, knowing that they have access to a reliable and well-characterized protein that will contribute to robust and accurate results.
The knowledgeable and responsive support team is dedicated to resolving issues and providing solutions that are tailored to specific experimental requirements.
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