Recombinant Human CLCF1 Protein, MYC/DDK-tagged
Cat.No. : | CLCF1-3242H |
Product Overview : | Recombinant Human CLCF1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 23.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | CLCF1 cardiotrophin-like cytokine factor 1 [ Homo sapiens ] |
Official Symbol : | CLCF1 |
Synonyms : | BSF-3; BSF3; CISS2; CLC; NNT-1; NNT1; NR6 |
Gene ID : | 23529 |
mRNA Refseq : | NM_001166212 |
Protein Refseq : | NP_001159684 |
MIM : | 607672 |
UniProt ID : | Q9UBD9 |
Products Types
◆ Recombinant Protein | ||
CLCF1-1413H | Recombinant Human CLCF1 Protein, GST-tagged | +Inquiry |
CLCF1-618H | Recombinant Human CLCF1 Protein, His-tagged | +Inquiry |
Clcf1-619M | Recombinant Mouse Clcf1 Protein, His-tagged | +Inquiry |
CLCF1-1716M | Recombinant Mouse CLCF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Clcf1-2178M | Recombinant Mouse Clcf1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
CLCF1-001HCL | Recombinant Human CLCF1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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