Recombinant Human CLDN22 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: CLDN22-142H
• Product Overview: CLDN22 MS Standard C13 and N15-labeled recombinant protein (NP_001104789) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 24.3 kDa
• AA Sequence: MALVFRTVAQLAGVSLSLLGWVLSC LTNYLPHWKNLNLDLNEMENWTMGL WQTCVIQEEVGMQCKDFDSFLALPA ELRVSRILMFLSNGLGFLGLLVSGF GLDCLRIGESQRDLKRRLLILGGIL SWASGVTALVPVSWVAHKTVQEFWD ENVPDFVPRWEFGEALFLGWFAGLS LLLGGCLLHCAACSSHAPLASGHYA VAQTQDHHQELETRNTNLKHTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CLDN22 claudin 22 [ Homo sapiens (human) ]
• Official Symbol: CLDN22
• Synonyms: CLDN22; claudin 22; CLDN21; claudin-22
• Gene ID: 53842
• mRNA Refseq: NM_001111319
• Protein Refseq: NP_001104789
• UniProt ID: Q8N7P3