Recombinant Human CLDN3 Protein, GST-tagged CLDN3-1442H

Recombinant Human CLDN3 Protein, GST-tagged

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Recombinant Human CLDN3 Protein, GST-tagged

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Cat.No. : CLDN3-1442H
Product Overview : Human CLDN3 full-length ORF ( AAH16056, 1 a.a. - 220 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 49.94 kDa
AA Sequence : MSMGLEITGTALAVL GWLGTIVCCALPMWR VSAFIGSNIITSQNI WEGLWMNCVVQSTGQ MQCKVYDSLLALPQD LQAARALIVVAILLA AFGLLVALVGAQCTN CVQDDTAKAKITIVA GVLFLLAALLTLVPV SWSANTIIRDFYNPV VPEAQKREMGAGLYV GWAAAALQLLGGALL CCSCPPREKKYTATK VVYSAPRSTGPGASL GTGYDRKDYV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CLDN3 claudin 3 [ Homo sapiens ]
Official Symbol : CLDN3
Synonyms : CLDN3; claudin 3; C7orf1, CPETR2; claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE R2; CPE receptor 2; HRVP1; RVP1; ventral prostate.1 like protein; CPE-R 2; CPE-receptor 2; ventral prostate.1-like protein; ventral prostate.1 protein homolog; C7orf1; CPE-R2; CPETR2;
Gene ID : 1365
mRNA Refseq : NM_001306
Protein Refseq : NP_001297
MIM : 602910
UniProt ID : O15551

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