|Product Overview :||Full-length extracellular domain of human CLEC11A cDNA (22 – 323 aa, derived from BC005810) was constructed with codon optimization and expressed with a small T7-His-TEV cleavage site Tag (29aa) fusion at its N-terminal. This protein is expressed in E.coli as inclusion bodies. The final product was refolded and chromatographically purified.|
|Description :||This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.|
|Source :||E. coli|
|AA Sequence :||MASMTGGQQMGRGHHHHHHENLYFQGGEFARGAEREWEGGWGGAQEEEREREALMLKHLQEALGLPAGRGDENPAGTVEGKEDWEMEEDQGEEEEEEATPTPSSGPSPSPTPEDIVTYILGRLAGLDAGLHQLHVRLHALDTRVVELTQGLRQLRNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKGLRLGHKCFLLSRDFEAQAAAQARCTARGGSLAQPADRQQMEALTRYLRAALAPYNWPVWLGVHDRRAEGLYLFENGQRVSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGTLENCVAQASDDGSWWDHDCQRRLYYVCEFPF|
|Purity :||> 90% by SDS-PAGE.|
|Applications :||1. May be used for in vitro -glycosylated CLEC11A protein mediated HSC regulation study with this protein as either coating matrix protein or as soluble factor.
2. May be used for CLEC11A protein – protein interaction assay.
3. May be used as enzymatic substrate for various proteases.
4. May be used for specific antibody production.
|Storage :||Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days.|
|Concentration :||0.5 mg/ml|
|Storage Buffer :||Sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.|
|Gene Name :||CLEC11A|
|Official Symbol :||CLEC11A C-type lectin domain containing 11A [ Homo sapiens (human) ]|
|Synonyms :||CLEC11A; C-type lectin domain containing 11A; P47; SCGF; LSLCL; CLECSF3; C-type lectin domain family 11 member A; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 3; C-type lectin superfamily member 3; lymphocyte secreted C-type lectin; lymphocyte secreted long form of C-type lectin; osteolectin; stem cell growth factor; stem cell growth factor; lymphocyte secreted C-type lectin|
|Gene ID :||6320|
|mRNA Refseq :||NM_002975|
|Protein Refseq :||NP_002966|
|UniProt ID :||Q9Y240|