Recombinant Human CLEC11A Protein, T7-His-TEV-tagged
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|Product Overview :||Full-length extracellular domain of human CLEC11A cDNA (22 – 323 aa, derived from BC005810) was constructed with codon optimization and expressed with a small T7-His-TEV cleavage site Tag (29aa) fusion at its N-terminal. This protein is expressed in E.coli as inclusion bodies. The final product was refolded and chromatographically purified.|
|Description :||This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.|
|Source :||E. coli|
|AA Sequence :||MASMTGGQQM GRGHHHHHHE NLYFQGGEFA RGAEREWEGG WGGAQEEERE REALMLKHLQ EALGLPAGRG DENPAGTVEG KEDWEMEEDQ GEEEEEEATP TPSSGPSPSP TPEDIVTYIL GRLAGLDAGL HQLHVRLHAL DTRVVELTQG LRQLRNAAGD TRDAVQALQE AQGRAEREHG RLEGCLKGLR LGHKCFLLSR DFEAQAAAQA RCTARGGSLA QPADRQQMEA LTRYLRAALA PYNWPVWLGV HDRRAEGLYL FENGQRVSFF AWHRSPRPEL GAQPSASPHP LSPDQPNGGT LENCVAQASD DGSWWDHDCQ RRLYYVCEFP F|
|Purity :||> 90% by SDS-PAGE.|
|Applications :||1. May be used for in vitro -glycosylated CLEC11A protein mediated HSC regulation study with this protein as either coating matrix protein or as soluble factor.
2. May be used for CLEC11A protein – protein interaction assay.
3. May be used as enzymatic substrate for various proteases.
4. May be used for specific antibody production.
|Storage :||Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days.|
|Concentration :||0.5 mg/ml|
|Storage Buffer :||Sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.|
|Gene Name :||CLEC11A|
|Official Symbol :||CLEC11A C-type lectin domain containing 11A [ Homo sapiens (human) ]|
|Synonyms :||CLEC11A; C-type lectin domain containing 11A; P47; SCGF; LSLCL; CLECSF3; C-type lectin domain family 11 member A; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 3; C-type lectin superfamily member 3; lymphocyte secreted C-type lectin; lymphocyte secreted long form of C-type lectin; osteolectin; stem cell growth factor; stem cell growth factor; lymphocyte secreted C-type lectin|
|Gene ID :||6320|
|mRNA Refseq :||NM_002975|
|Protein Refseq :||NP_002966|
|UniProt ID :||Q9Y240|
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