Recombinant Human CLIC1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CLIC1-5937H
• Product Overview: CLIC1 MS Standard C13 and N15-labeled recombinant protein (NP_001279) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 26.7 kDa
• AA Sequence: MAEEQPQVELFVKAGSDGAKIGNCP FSQRLFMVLWLKGVTFNVTTVDTKR RTETVQKLCPGGQLPFLLYGTEVHT DTNKIEEFLEAVLCPPRYPKLAALN PESNTAGLDIFAKFSAYIKNSNPAL NDNLEKGLLKALKVLDNYLTSPLPE EVDETSAEDEGVSQRKFLDGNELTL ADCNLLPKLHIVQVVCKKYRGFTIP EAFRGVHRYLSNAYAREEFASTCPD DEEIELAYEQVAKALKTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CLIC1 chloride intracellular channel 1 [ Homo sapiens (human) ]
• Official Symbol: CLIC1
• Synonyms: CLIC1; chloride intracellular channel 1; chloride intracellular channel protein 1; NCC27; p64CLCP; hRNCC; RNCC protein; chloride channel ABP; nuclear chloride ion channel 27; nuclear chloride ion channel protein; regulatory nuclear chloride ion channel protein; G6
• Gene ID: 1192
• mRNA Refseq: NM_001288
• Protein Refseq: NP_001279
• MIM: 602872
• UniProt ID: O00299