Recombinant Human COTL1, GST-tagged

• Cat.No.: COTL1-11483H
• Product Overview: Recombinant Human COTL1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-142a.a.
• Description: This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: COTL1 coactosin-like 1 (Dictyostelium) [ Homo sapiens ]
• Official Symbol: COTL1
• Synonyms: COTL1; coactosin-like 1 (Dictyostelium); coactosin-like protein; CLP; FLJ43657; MGC19733
• Gene ID: 23406
• mRNA Refseq: NM_021149
• Protein Refseq: NP_066972
• MIM: 606748
• UniProt ID: Q14019
• Chromosome Location: 16q24.1
• Function: actin binding; enzyme binding; protein binding