Recombinant Human COTL1 Protein, GST-tagged

• Cat.No.: COTL1-1730H
• Product Overview: Human COTL1 full-length ORF ( AAH10884, 1 a.a. - 142 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 41.36 kDa
• AA Sequence: MATKIDKEACRAAYNLVRDDGSAVI WVTFKYDGSTIVPGEQGAEYQHFIQ QCTDDVRLFAFVRFTTGDAMSKRSK FALITWIGENVSGLQRAKTGTDKTL VKEVVQNFAKEFVISDRKELEEDFI KSELKKAGGANYDAQTE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COTL1 coactosin-like 1 (Dictyostelium) [ Homo sapiens ]
• Official Symbol: COTL1
• Synonyms: COTL1; coactosin-like 1 (Dictyostelium); coactosin-like protein; CLP; FLJ43657; MGC19733
• Gene ID: 23406
• mRNA Refseq: NM_021149
• Protein Refseq: NP_066972
• MIM: 606748
• UniProt ID: Q14019