Recombinant Human CXCL9 (MIG)
Cat.No. : | CXCL9-72H |
Product Overview : | Human CXCL9/MIG was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified. |
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- Gene Information
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Description : | Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family. It is also commonly known as Monokine Induced by Gamma interferon (MIG). CXCL9 (MIG) is a T-cell chemoattractant, which is induced by IFN-gamma. It is closely related to two other CXC chemokines -CXCL10 and CXCL11. There have been 17 different C-X-C chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes. CXCL9 (MIG) elicits its effects by binding to the cell surface chemokine receptor CXCR3. |
Source : | Yeast |
Species : | Human |
Form : | Lyophilized |
Molecular Mass : | 11.7 kDa |
AA Sequence : | TPVVRKGRCS CISTNQGTIH LQSLKDLKQF APSPSCEKIE IIATLKNGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK VRKSQRSRQK KTT (103) |
Applications : | The human CXCL9/MIG protein can be used in cell culture, as a CXCL9/MIG ELISA Standard, and as a Western Blot Control. |
Storage : | -20 C |
Gene Name : | CXCL9 chemokine (C-X-C motif) ligand 9 [ Homo sapiens ] |
Official Symbol : | CXCL9 |
Synonyms : | CXCL9; chemokine (C-X-C motif) ligand 9; CMK, MIG, monokine induced by gamma interferon; C-X-C motif chemokine 9; crg 10; Humig; SCYB9; small-inducible cytokine B9; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma; CMK; MIG; crg-10; |
Gene ID : | 4283 |
mRNA Refseq : | NM_002416 |
Protein Refseq : | NP_002407 |
MIM : | 601704 |
UniProt ID : | Q07325 |
Chromosome Location : | 4q21 |
Pathway : | CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | chemokine activity; cytokine activity; |
Products Types
◆ Recombinant Protein | ||
Cxcl9-2399M | Active Recombinant Mouse Cxcl9 Protein | +Inquiry |
CXCL9-076C | Active Recombinant Human CXCL9 Protein (103 aa) | +Inquiry |
CXCL9-68H | Active Recombinant Human CXCL9 Protein | +Inquiry |
CXCL9-2761H | Recombinant Human CXCL9 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cxcl9-126M | Active Recombinant Mouse Cxcl9 Protein | +Inquiry |
◆ Native Protein | ||
CXCL9-30233TH | Native Human CXCL9 | +Inquiry |
◆ Lysates | ||
CXCL9-7165HCL | Recombinant Human CXCL9 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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