Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human CXCL9 protein

Cat.No. : CXCL9-17H
Product Overview : Recombinant Human CXCL9 protein was expressed in Escherichia coli.
  • Specification
  • Gene Information
  • Related Products
Description : CXCL9 is a T-cell chemoattractant induced by IFN-γ belonging to the CXC chemokine family and it is also known as Monokine induced by gamma interferon (MIG). CXCL9 is closely related to two other CXC chemokines called CXCL10 and CXCL11 and they all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3. CXCL9 is a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response and chemotactic for activated T-cells. Recombinant human CXCL9 contains 103 amino acids which is a single non-glycosylated polypeptide chain. The human CXCL9 shares 75 % and 67 % a.a. sequence identity with mouse and rat CXCL9.
Source : E.coli
Species : Human
Form : Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB, pH 7.4, 50 mM NaCl.
Bio-activity : Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is in a concentration range of 10-100 ng/ml.
Molecular Mass : Approximately 11.7 kDa, a single non-glycosylated polypeptide chain containing 103 amino acids.
Protein length : 103
AA Sequence : TPVVRKGRCSCISTNQGTIHLQSLK DLKQFAPSPSCEKIEIIATLKNGVQ TCLNPDSADVKELIKKWEKQVSQKK KQKNGKKHQKKKVLKVRKSQRSRQK KTT
Endotoxin : Less than 1 EU/μg of rHuMIG/CXCL9 as determined by LAL method.
Purity : >97% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : CXCL9
Official Symbol : CXCL9
Synonyms : CXCL9; chemokine (C-X-C motif) ligand 9; CMK, MIG, monokine induced by gamma interferon; C-X-C motif chemokine 9; crg 10; Humig; SCYB9; small-inducible cytokine B9; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma; CMK; MIG; crg-10;
Gene ID : 4283
mRNA Refseq : NM_002416
Protein Refseq : NP_002407
MIM : 601704
UniProt ID : Q07325

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
What is the relationship between CXCL9 and the chemokine receptor CXCR3? 08/16/2022

CXCL9 can bind specifically to CXCR3 and accumulate at sites of inflammation, thereby inducing and exacerbating the inflammatory response.

Do you offer CXCL9 fused with other tags? 01/25/2022

Yes, we will provide you with the most suitable labels according to your experimental needs.

Can CXCL9 be detected in lymphoid tissue under normal physiological conditions? 11/23/2020

No, CXCL9 can only be detected when the organism is inflamed or infected.

CXCL9 is secreted by which cells? 11/21/2020

CXCL9 is mainly secreted by endothelial cells and monocytes.

What diseases has CXCL9 been closely associated with the study of? 10/19/2020

CXCL9 has been linked to pulmonary embolism, asthma and breast cancer research.

Customer Reviews (2)

Write a review
Reviews
02/21/2023

    Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

    04/01/2022

      The protein composition was stable and the concentration was high, which allowed me to obtain satisfactory experimental results.

      Ask a Question for All CXCL9 Products

      Required fields are marked with *

      My Review for All CXCL9 Products

      Required fields are marked with *

      0

      Inquiry Basket

      cartIcon
      logo

      FOLLOW US

      Terms and Conditions        Privacy Policy

      Copyright © 2024 Creative BioMart. All Rights Reserved.

      Contact Us

      • /

      Stay Updated on the Latest Bioscience Trends