Recombinant Human DDIT3 Protein, GST/His-tagged


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Recombinant Human DDIT3 Protein, GST/His-tagged

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Cat.No. : DDIT3-217H
Product Overview : Recombinant Human DDIT4L fused with N-terminal GST and C-terminal His was expressed in E. coli.
Description : This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Source : E. coli
Species : Human
Tag : GST/His
Form : 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl.
Molecular Mass : 45 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : DDIT3 DNA-damage-inducible transcript 3 [ Homo sapiens ]
Official Symbol : DDIT3
Synonyms : DDIT3; DNA-damage-inducible transcript 3; DNA damage-inducible transcript 3 protein; C/EBP zeta; CHOP; CHOP10; GADD153; DDIT-3; c/EBP-homologous protein 10; CCAAT/enhancer-binding protein homologous protein; growth arrest and DNA damage-inducible protein GADD153; CEBPZ; CHOP-10; MGC4154;
Gene ID : 1649
mRNA Refseq : NM_004083
Protein Refseq : NP_004074
MIM : 126337
UniProt ID : P35638
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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