Recombinant Human DIRAS3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DIRAS3-4624H
• Product Overview: DIRAS3 MS Standard C13 and N15-labeled recombinant protein (NP_004666) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 25.9 kDa
• AA Sequence: MGNASFGSKEQKLLKRLRLLPALLI LRAFKPHRKIRDYRVVVVGTAGVGK STLLHKWASGNFRHEYLPTIENTYC QLLGCSHGVLSLHITDSKSGDGNRA LQRHVIARGHAFVLVYSVTKKETLE ELKAFYELICKIKGNNLHKFPIVLV GNKSDDTHREVALNDGATCAMEWNC AFMEISAKTDVNVQELFHMLLNYKK KPTTGLQEPEKKSQMPNTTEKLLDK CIIMTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DIRAS3 DIRAS family GTPase 3 [ Homo sapiens (human) ]
• Official Symbol: DIRAS3
• Synonyms: DIRAS3; DIRAS family, GTP-binding RAS-like 3; ARHI, ras homolog gene family, member I; GTP-binding protein Di-Ras3; NOEY2; ras homolog gene family, member I; rho-related GTP-binding protein RhoI; distinct subgroup of the Ras family member 3; ARHI
• Gene ID: 9077
• mRNA Refseq: NM_004675
• Protein Refseq: NP_004666
• MIM: 605193
• UniProt ID: O95661