| Cat.No. : |
DOCK1-2802H |
| Product Overview : |
Human DOCK1 full-length ORF ( AAH84559.1, 1 a.a. - 152 a.a.) recombinant protein with GST-tag at N-terminal. |
| Description : |
This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
43.6 kDa |
| AA Sequence : |
MRIGRQSCKI HNYAINNGLF FKCMISPPSG DVRNDIYVTL VQGDFDKGSK TTAKNVEVTV SVYDEDGKRL EHVIFPGAGD EAISEYKSVI YYQVKQPRWF ETVKVLFTWS FYHMALIMKC SFVTQGNILT SSSARELLQA GRVSPNKVIQ GC |
| Applications : |
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Quality Control Testing : |
12.5% SDS-PAGE Stained with Coomassie Blue.
|
